Purification and Biochemical Properties of Human Plasminogen

Purification and biochemical properties of human plasminogen.

Plasminogen is the plasma precursor of the fibrinolytic enzyme, plasmin. The activation of plasminogen isolated from various animal species by streptokinase, a protein of bacterial origin, has received considerable attention in recent years. A two-step reaction has been postulated wherein streptokmase reacts with a substance termed proactivator (1)) which is present in highest concentration in ...

The purification and properties of human plasminogen.

Billimoria, J. D., Curtis, R. G. & Maclagan, N. F. (1960). Biochem. J. 78, 185. Curragh, E. F. & Elmore, D. T. (1962). J. chem. Soc. p. 2948. Curragh, E. F. & Elmore, D. T. (1963). Biochem. J. 86, 9P. Ebata, M. (1961). J. Biochem., Tokyo, 49, 110. Ehrenpreis, S. & Scheraga, H. A. (1957). J. biol. Chem. 227, 1043. Elmore, D. T., Kingston, A. E. & Shields, D. B. (1963). J. chem. Soc. p. 2070. Elm...

Purification of human plasminogen.

Biochemical properties of plasminogen activator inhibitor-1.

PAI-1 is a Mr ~50,000 glycoprotein, which is the primary physiological inhibitor of the two plasminogen activators uPA and tPA. PAI-1 belongs to the serpin protein family. Studies of PAI-1 have contributed significantly to the elucidation of the protease inhibitory mechanism of serpins, which is based on a metastable native state becoming stabilised by insertion of the RCL into the central beta...

some properties of fuzzy hilbert spaces and norm of operators

in this thesis, at first we investigate the bounded inverse theorem on fuzzy normed linear spaces and study the set of all compact operators on these spaces. then we introduce the notions of fuzzy boundedness and investigate a new norm operators and the relationship between continuity and boundedness. and, we show that the space of all fuzzy bounded operators is complete. finally, we define...